Vyvanse, the brand name for lisdexamfetamine, is a central nervous system (CNS) stimulant most often prescribed to manage attention-deficit hyperactivity disorder (ADHD) in both adults and children. It can also be used to treat moderate to severe binge eating disorder, and some doctors prescribe it “off-label” for narcolepsy and other sleep-related issues. Vyvanse is a Schedule II controlled substance, reflecting its legitimate therapeutic benefits but also its considerable potential for physical or psychological dependence. If a person develops dependence on Vyvanse, they may experience withdrawal upon quitting. Vyvanse withdrawal symptoms vary between individuals and can interrupt normal functioning, prompting mood or behavioral changes that sometimes call for professional help.
Vyvanse Crash vs. Vyvanse Withdrawal
Certain stimulants may cause a “crash” that lasts for several days when taken in large amounts. A crash typically involves intense fatigue and prolonged sleep, especially following the misuse of short-acting stimulants like methamphetamine. Unlike these short-acting drugs, Vyvanse is long-acting, and there is no strong indication that a crash occurs with long-acting stimulants. For that reason, concerns about preventing a Vyvanse crash are less common compared to issues that can arise with short-acting stimulants. However, all stimulant drugs — including Vyvanse — can trigger withdrawal symptoms if use stops abruptly after taking a high dose.
How To Avoid the Vyvanse Crash
Using a long-acting stimulant such as Vyvanse inherently lowers your risk of experiencing a crash, as short-acting stimulants are more strongly associated with crashes. Because Vyvanse exerts its effects gradually, it is considered less likely to produce a drastic come-down phase that might be defined as a crash.
Vyvanse Withdrawal
Stimulant withdrawal symptoms can emerge once the body and brain adapt to the consistent presence of a stimulant and then suddenly lose access to it. When Vyvanse use is significantly reduced or halted, the brain must rebalance the levels of dopamine and norepinephrine that have been artificially elevated by the medication. This shift can produce withdrawal symptoms as the brain adjusts to lower levels of these neurotransmitters.
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Vyvanse Withdrawal Symptoms
Withdrawal symptoms for Vyvanse generally mirror those associated with other stimulant drugs. The most commonly reported symptoms include:
- Fatigue
- Cognitive slowing
- Sleep disturbances
- Vivid dreams or nightmares
- Sleep disturbances
- Increased appetite
- Agitation
- Fatigue
- Physical discomfort
- Depression
Those who take overly high doses of Vyvanse may also encounter more severe withdrawal effects, such as:
- Psychosis
- Disorganized thought patterns
- Hallucinations
- Paranoia
It is also important to watch for the return of symptoms that Vyvanse was originally prescribed to address. Individuals with ADHD or binge eating disorder might see a resurgence of their original symptoms if they suddenly stop Vyvanse. Consult a doctor if you notice such changes.
Vyvanse Withdrawal Timeline
Withdrawal typically starts within a few days of discontinuing Vyvanse use, and most symptoms resolve within two weeks. However, not everyone will experience withdrawal, so there is no formal manufacturer recommendation to taper Vyvanse. Each person’s physiology and drug use history are unique, which can affect the onset and duration of withdrawal.
How To Quit Vyvanse
Before stopping Vyvanse, it is crucial to consult your healthcare provider, especially if you rely on Vyvanse to manage ADHD or binge eating disorder. Ceasing Vyvanse abruptly can result in the sudden return or worsening of these underlying conditions. Keeping your doctor informed allows them to keep an eye on your health during and after discontinuation.
Is It Safe to Quit Vyvanse Cold Turkey?
In certain cases, it may be possible to stop Vyvanse abruptly without tapering. This is partly because Vyvanse is a long-acting medication that exits the body gradually, reducing the abrupt jolt to the system. Its half-life (the time needed for half of the drug to leave the bloodstream) generally ranges from 8.6 to 11.3 hours, meaning it takes roughly five half-lives (close to a week) for the body to eliminate the drug completely.
However, for individuals taking large doses or with a history of withdrawal symptoms, doctors may advise a slower reduction or taper rather than quitting all at once. This gradual reduction can lower the risk of severe withdrawal effects.
Weaning or Tapering Off Vyvanse
A taper involves reducing your Vyvanse dosage incrementally to give the body time to adapt. Not everyone needs a Vyvanse taper, but in certain cases — particularly at higher doses, such as above the recommended maximum of 70 mg daily — tapering might be beneficial. Although few clinical studies focus on Vyvanse taper schedules, one study showed that individuals on extremely high doses (150 mg or more) were tapered to 50 mg for one week before discontinuing use entirely.
Medical Detox for Vyvanse Withdrawal
Unlike some drugs, there are no officially approved medications to treat Vyvanse withdrawal or curb the cravings linked to CNS stimulants. However, a medically supervised detox still offers important benefits. Professionals can guide you through psychological challenges that may arise and supply over-the-counter medications to alleviate discomfort from headache, body aches, or nausea. Such care allows you to concentrate on recovery and lowers the likelihood of relapse.
How Long Does It Take To Detox From Vyvanse?
Withdrawal symptoms typically begin a few days after the last dose and generally improve within two weeks. Medical detox might last anywhere from a handful of days to roughly two weeks, based on an individual’s situation. At The Recovery Village Salem, for example, the average person spends 5–10 days in medical detox.
Find a Detox Center Near You
Overcoming a Vyvanse addiction may be challenging, but it is possible with the right support. The Recovery Village Salem provides comprehensive, customized treatment plans for individuals struggling with Vyvanse dependency or co-occurring conditions. If you’re ready to begin your journey to a healthier life, contact us today to learn more about our treatment programs and how we can help you thrive without Vyvanse. You deserve a brighter future.