Percocet is a prescription pain reliever containing a combination of oxycodone, an opioid analgesic, and acetaminophen, a non-opioid pain reliever. It is commonly prescribed to treat moderate to severe pain, often following surgery or injury. While Percocet can be highly effective for pain management, it carries a significant risk of dependence and addiction. When someone with physical dependence on Percocet suddenly stops taking it or significantly reduces their dosage, withdrawal symptoms are likely to occur. Understanding the withdrawal process and timeline can help individuals prepare for the journey toward recovery.
Below is an overview of the common Percocet withdrawal symptoms, how the withdrawal timeline typically progresses, and why professional help—such as from The Recovery Village Salem—can be crucial in safely navigating the process.
What Is Percocet Dependence?
Long-term or excessive use of opioids can cause a person’s brain chemistry to change. Over time, the brain adapts to the presence of opioids, and the body develops a physical dependence. This means that when the drug is withheld, the body reacts negatively, leading to withdrawal symptoms. Even people who take Percocet exactly as prescribed over a longer period may become physically dependent on it.
When someone stops using Percocet suddenly, the body needs time to reestablish its balance without the constant influence of opioids. In this transitional period, withdrawal symptoms may arise. Although it can be uncomfortable and at times painful, withdrawal is a normal process that signals the body is adjusting to functioning without opioids.
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Common Percocet Withdrawal Symptoms
Withdrawal symptoms can vary in intensity from person to person, often influenced by factors such as an individual’s metabolism, overall health, dosage levels, and duration of use. Common withdrawal symptoms include:
- Flu-like Discomfort: Many people describe withdrawal from opioids as feeling like a severe flu. Common physical symptoms include muscle aches, chills, and a runny nose.
- Gastrointestinal Distress: Nausea, vomiting, diarrhea, and abdominal cramps are frequently reported. These symptoms can contribute to dehydration and electrolyte imbalances if not properly addressed.
- Mood Swings and Irritability: The absence of opioids can lead to irritability, anxiety, agitation, and restlessness. Emotional volatility is common in the early stages of withdrawal.
- Insomnia and Sleep Disturbances: Falling asleep and staying asleep can be challenging during withdrawal, partly due to anxiety and general discomfort.
- Excessive Sweating and Yawning: Sweating profusely, especially at night, and uncontrollable yawning are also characteristic signs of opioid withdrawal.
- Elevated Heart Rate and Blood Pressure: Opioids typically slow certain bodily functions. When the substance is removed, people may experience an increase in heart rate and blood pressure.
- Cravings: Intense cravings for Percocet or other opioids often arise as the body seeks a return to the state of equilibrium it felt during opioid use.
While these symptoms can be quite uncomfortable, most acute withdrawal symptoms are not life-threatening. However, complications, such as dehydration or related medical issues, can develop if left unmanaged.
Percocet Withdrawal Timeline
The precise timeline for Percocet withdrawal can vary depending on factors such as body composition, metabolism, duration of use, and dosage level. Generally, though, because oxycodone is relatively short-acting, withdrawal symptoms can begin within a few hours of the last dose and may follow this pattern:
6–12 Hours After the Last Dose
- Early, milder symptoms typically emerge.
- Muscle aches, restlessness, irritability, and anxiety are common.
- Minor flu-like symptoms, such as a runny nose or watery eyes, can appear.
24–48 Hours After the Last Dose
- Symptoms often intensify and reach their peak.
- More pronounced flu-like symptoms, increased sweating, body aches, and gastrointestinal upset may occur.
- Sleep disturbances, agitation, and strong cravings can be prevalent.
3–5 Days After the Last Dose
- By this point, symptoms may begin to gradually subside but can still be challenging.
- Nausea and diarrhea may start to diminish, but fatigue and mood swings may persist.
- Cravings can remain strong, as the body and mind continue to adjust.
1–2 Weeks After the Last Dose
- Most acute withdrawal symptoms lessen significantly.
- Some individuals experience lingering symptoms, such as mild anxiety, mood swings, or low energy.
- Psychological symptoms, including cravings, may persist and can benefit from ongoing treatment and support.
Post-Acute Withdrawal Syndrome (PAWS)
- Some individuals may develop ongoing issues like insomnia, irritability, depression, or cravings for weeks or months after stopping opioid use.
- These symptoms are known as Post-Acute Withdrawal Syndrome and underline the importance of continued medical and psychological support.
Seeking Professional Help for Percocet Withdrawal
While some people attempt to quit Percocet “cold turkey” at home, it is generally safer and more comfortable to undergo withdrawal under professional medical supervision. The Recovery Village Salem offers a range of programs to help individuals detox and recover from opioid use disorders in a safe, supportive environment. Medical professionals can monitor for complications, manage dehydration or other health concerns, and offer supportive medications to alleviate the severity of withdrawal symptoms.
- Medical Detoxification: In a medical detox program, individuals have access to care providers around the clock. Supportive medications can be used to manage opioid withdrawal symptoms, reduce cravings, stabilize vitals, and address co-occurring mental health disorders if present. Having a team of professionals ready to intervene can improve comfort and outcomes.
- Medication-Assisted Treatment (MAT): After detox, some individuals benefit from medication-assisted treatment, which may include drugs like buprenorphine or methadone. These medications work by binding to the same receptors in the brain that opioids target, helping reduce cravings and withdrawal symptoms in a controlled manner.
- Therapy and Counseling: Because opioid use disorder impacts both physical and emotional well-being, comprehensive treatment includes addressing underlying psychological factors. Cognitive-behavioral therapy (CBT), individual counseling, group therapy, and family therapy are integral parts of the recovery process. These methods help individuals develop coping skills, build resilience, and form healthier support networks.
- Aftercare and Ongoing Support: Recovery from Percocet addiction doesn’t end when acute withdrawal symptoms subside. Ongoing support programs—such as outpatient therapy, peer support groups (like NA or SMART Recovery), and alumni programs—provide continued accountability and assistance, helping individuals maintain long-term sobriety.
Medical Detox for Opioids at The Recovery Village Salem
Percocet withdrawal can be a challenging process, with symptoms ranging from flu-like body aches to powerful cravings. While the discomfort can be significant, it’s important to remember that withdrawal is a necessary step in breaking free from physical dependence on opioids. By understanding the typical withdrawal timeline and seeking professional support—such as at The Recovery Village Salem—individuals can significantly increase their chances of success. Through evidence-based treatment, counseling, and ongoing support, recovery from Percocet addiction is possible, paving the way for a healthier and more fulfilling life.
If you or someone you care about is experiencing Percocet dependency, don’t hesitate to reach out to our Recovery Advocates for help. The sooner you begin treatment, the better your chances for a safe and successful recovery.
